Hello,
I have the same problem with high DPC latency from ndis.sys and tcpip.sys. The issue appears to be only on Windows 10, reproducible with various driver versions released from a year ago up until v21.0.
My Motherboard is also an ASUS model, ASUS Maximus VIII Hero Z170. The problem appears both on ASUS' own drivers that I downloaded from their site and the drivers from Intels website.
I have contacted them to see if the issue is on their end and they've said they don't make any NIC customization (at least not on my motherboard model). The response is the same as posted by another user here: Re: intel nic drivers 19.3 huge 6000+ dpc latency spike once a few secs (that thread also mentions this issue on later posts from page ~10 onward).
Currently, I'm running Windows 10 Anniversary update and experience the problem described here, but it was also was present on Windows 10 RTM and Threshold 2. Driver version currently installed is 12.15.23.1 (latest from Intel website).
Curiously, the same issue is present on systems with different NICs (Realtek etc.) in conjunction with Windows 10, so it looks like NIC manufacturers will need to work with Microsoft on resolving this annoying issue.
The only fix currently is to use Windows 8.1 or 7, in some cases buying a 3rd party USB Ethernet adapter solves the issue.